
Marion opened by telling us that her talk would be about ornamental and native plants – their history, their less well-known aspects and their ability to both heal and harm. The definition of ‘poisonous’ can range from a nettle sting to causing death. The talk would cover just some of the plants that can be described as poisonous, highlighting those that can be both good and bad.
A good example is the yew tree. All parts of the tree are poisonous, apart from the red flesh of the berries. Symptoms of poisoning can range from stomach upset to heart failure. There are records of yew clippings being thrown into a field where sheep then died after eating them. Traditionally, yew trees have been grown in churchyards and in that environment there are many ancient specimens – in Perthshire there is a tree recorded as being between two and three thousand years old. It was believed that yew trees became poisonous by feeding on the dead bodies buried in the ground in the churchyards, and for that reason they also became associated with witches (another theme in this talk). On the positive side, yew has more recently become known as the source of the anti-cancer chemical taxane, which has had many benefits.
A number of gardens were sources of information for this talk – the Chelsea Physic Garden, the Alnwick Garden Poison Garden and the Welsh National Botanic Garden. The latter contains the Apothecary Hall, a recreation of an apothecary’s shop as it would have been in 1919. Many herbal plants include ‘officinalis’ in their Latin name, indicating that they were used for medicinal purposes, primarily at home. If these domestic remedies failed, people would turn to the apothecary., who would have turned plants into powders, pills and tinctures – the raw materials would be contained in labelled drawers. An example photograph from the Apothecary Hall showed us a drawer labelled with various plants we would consider poisonous, including Aconite. The latter ingredient was included in a prescription (which can be seen there) dated 23 June 1918 – but we don’t know what was wrong with the patient, nor whether they recovered!
Plants are, of course, still used in medicine; now, much more rigorous testing and isolation of the active ingredient is carried out. This ingredient is then made up or synthesised (created artificially). The World Health Organisation estimates that 80% of the world’s population rely on plant-based remedies, while 40% of the industrialised countries use medicines based on plant extracts, and 33% of new medicines developed in the last 25 years have been made from or are synthesised versions of plants. For example, the anti-malarial ingredient artemisinin was isolated in Artemisia annua (sweet wormwood) in the 1970s which was effective, but then resistance developed. However, now an American trial is using the whole plant, which contains 10 different anti-malarial properties, which is proving very effective (as it is harder for the parasite to develop resistance to 10 different components).
The poisonous ingredients found in plants fall into a number of groups:
Alkaloids: this group includes the poppy, which provides morphine.
Glycosides: this group includes foxgloves, whose active ingredient is used to treat heart problems.
Saponins: only some plants containing these are poisonous. The group includes the soapworts, but also the little corncockle, which used to be a problem in hayfields.
Essential oils (terpenes and sesquiterpenes): many of us are familiar with the great variety of essential oils available. One example is lemon balm essential oil which is now being studied for the treatment of agitation and aggression in Alzheimer’s Disease, and also for the treatment of epilepsy. Essential oils are widely available, but as they are very concentrated they can be problematic if they are not correctly diluted.
Peptides and Proteins: peptides (as found in gardenia, for example,) are widely used in skincare preparations.
Pyrethrins and Pyrethroids: deriving from plants from the Chrysanthemum family, pyrethrum is an insecticide (used against ants, for example). Care should be taken to use it in the evening to avoid damaging other insects such as bees.
There are three ways in which a person may be killed by a plant:
- they may ingest it accidentally;
- they may be given the plant with intent to kill them;
- they may self-administer it.
There are a number of plant families which contain poisonous plants (although not all the plants in the family may be poisonous:
Solanaceae: this family contains potatoes (which is why you should cut out any parts of potatoes with green colour for the high concentration of glycoalkaloids) but also deadly nightshade; it contains Nicotiana tabacum (tobacco), as well as the lovely scented N. sylvestnis.
Apiaceae: this is the carrot family, so again it contains a vegetable that we eat as well as hemlock (Socrates was sentenced to die by drinking hemlock). Its similarity to wild carrot means great care should be exercised. Giant hogweed, in the same family, is phytotoxic, and so the juice can cause severe blistering and burns when exposed to sunlight. Dill, parsley and parsnip also have the potential to be skin irritants.
Ranunculaceae: this is the buttercup family, including Aconitum (all parts of which are extremely poisonous), Delphinium and Helleborus (which has irritant sap).
Liliaceae: cat-owners will no doubt be aware of the danger these plants pose to cats. All parts of the plant are toxic to cats, including the leaves, flowers and pollen, even in very small amounts. The autumn crocus (Colchicum autumnal) is also a toxic plant, but is used in the treatment of gout.
Papaveraceae: this is the poppy family, which is the source of the painkillers morphine and codeine with all their adverse and beneficial effects.
Euphorbiaceae: many of the spurges contain irritant sap which is phytotoxic. The castor-oil plant, Ricinus communis, is a member, giving us castor oil (used for many things including the promotion of hair growth in men, but also the deadly poison ricin). It is the coating of the bean that contains the most ricin – one bean contains enough to kill a human, and it would take four beans to kill a horse.
Amaryllidaceae: two plants in this family very familiar to us in Wales are the daffodil and the snowdrop. Both plants contain galantamine, which is used in the treatment of Alzheimer’s Disease in its early stages. Indeed, daffodils are grown commercially for this purpose, including near Talgarth in the Brecon Beacons. Bluebells are another member of this family, everywhere in the hedgerows and woods at this time of year, with a medical history going back to the thirteenth century for the treatment of leprosy. Bluebells are now being investigated as a possible control for mycobacterial infections, including tuberculosis. It is known that badgers eat bluebells, so is it possible that they are self-medicating for tuberculosis? Bluebell bulbs have been shown to contain at least 15 different compounds, some of which are similar to those used in the treatment of HIV and cancer, and others have diuretic and astringent properties. On a more mundane note, the juice from bluebell bulbs was traditionally used in place of starch.
Plantaginaceae: an important plant in this family is the foxglove, which contains digitoxin and digitalin. These are compounds which have a low therapeutic index (where there is only a narrow margin between the amount needed to be medically effective and the amount that would do harm). Despite being so well-known to us today, its use to treat heart disease is relatively recent. In 1598, Gerard in his Herbal declared that the foxglove had no place in medicine; although it would have been used by wise women to treat throat problems based on the doctrine of signatures. It was also later used as a diuretic to treat dropsy (which in retrospect makes sense as fluid build-up can be caused by congestive heart failure).
Marion went on to discuss some of the plants, whether native or introduced, which might serve as starter plants in a witch’s garden. The first four have been referenced in the context of the ‘witches’ flying brew’, supposedly used by witches before mounting their broomsticks!
The first is Aconitum, or wolfsbane. It has the reputation of being one of the most poisonous plants in the garden (although it is also a wild plant). It can be absorbed even through broken skin. It can give rise to severe stomach problems and slow the heart, sometimes fatally. Gloves should always be worn when handling the plant. It was used in warfare to poison arrow tips and to poison the water supplies of besieged castles; it was also used to administer the death penalty in some Greek cities.
Another ingredient in this brew was Atropa belladonna, or deadly nightshade, named after Atropos who in Greek mythology wields the scissors of death. Poisonous as it is, atropine is also an antidote to the nerve agent sarin, and was issued as such to US troops in the Iraq war. The ‘belladonna’ in the name comes from the Italian for ‘beautiful woman’ and refers to its use in dilating pupils to make eyes appear more attractive; atropine is still in use in optometry for specific purposes.
A second member of the nightshade family is henbane, Hyoscyamus niger, containing hyoscine causing hallucinations, as well as vision problems, forgetfulness, weakness and sleepiness. Along with the mandrake root, again of the same family and containing hyoscine, it also makes up part of the flying brew.
Datura, thornapple or jimsonweed, is another plant with a low therapeutic index. The plant has been used as an anaesthetic and asthma treatment, as well as a hallucinogenic. It is worth noting that Brugmansia, often grown in gardens, has the same properties.
Amongst other plants is Sambucus nigra , the elder. In addition to being used to create elderflower cordial and elderberry wine, both flowers and berries have anti-bacterial and anti-viral properties. However, the roots and some parts are very poisonous, so care is needed. Elder trees were often planted in graveyards, and were believed to be protective if planted by a house. In Ireland witches traditionally rode eldersticks rather than broomsticks; the most powerful wand in the Harry Potter books was the Elder Wand.
The box, or Buxus sempervirens, is a native plant commonly used for edging in gardens, but it also contains buxine and is poisonous to us (it can cause a skin rash) and animals. Boxwood extract may boost the immune system, and it was once used in place of quinine to reduce a fever.
Marion was keen to stress that the purpose of her talk had not been to make us concerned, but to bring out the hidden elements behind the history of many plants which she hoped would add to our enjoyment of plants. Members of the audience shared their experiences of contact with some of the plants she had mentioned, and the meeting closed with a big thank you to Marion for a fascinating and enjoyable talk.
Members Only – Mad Hatters Tea Party
Cothi Gardeners’ Club members are invited to a Mad Hatters Tea Party (hats obligatory, the madder the better!) on 14 June at Fiona and Julian’s wonderful garden in Rhydcymerau, when the wild flower meadow should be at its best. If you are a member, and haven’t already let Elena know that you would like to be there, please get in touch with her directly, or email Cothi Gardeners and I will forward your query on. Julian has very kindly prepared a couple of videos to introduce the garden to new members of the club and remind existing members of its delights.